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Catechin attenuates neuronal apoptosis in the cortex and hippocampus induced by TBI by downregulating Bax, cleaved caspase-3 expression, and upregulating Bcl-2 levels ( Catechin administration increases hippocampal neurogenesis in the subgranular zone, contributing to cognitive recovery following TBI (Z

Kovanda et al., 2019

Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, et al

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Importantly, it has also been shown that placental 3-THP insufficiency in mice leads to cerebellar myelination impairment after birth, which correlated with autistic-like behavior in male offspring (119)